British Journal of Haematology Wiley Online Library Frontiers The global role of G6PD in infection and immunity In G6PD deficiency (XR), we have increased oxidative damage to RBCs, leading to intravascular hemolysis with decreased serum haptoglobin. We have decreased NADPH production, which means decreased conversion of oxidized ( S S ) glutathione Pathology of G6PD deficiency Pathology Made Simple Glucose 6 Phosphate Dehydrogenase Deficiency Hematology & Oncology UWorld Medical Library
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