Glucose 6 Phosphate Dehydrogenase an overview ScienceDirect Topics Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black Blister Cell in G6PD Deficiency , Red Blood Cell with a clear vacuole like area on its membrane, resembling a blister., It usually results when splenic macrophages remove precipitated Heinz Role of G6PD in managing oxidative stress Glutathione peroxidase Download Scientific Diagram G6PD Deficiency and G6PD Activity Testing Mindray