Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Recent Progress and Advances in HGF MET Targeted Therapeutic Agents for Cancer Treatment The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases ScienceDirect The Therapeutic Targeting of HGF c Met Signaling in Hepatocellular Carcinoma: Alternative Approaches HGF c Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR NGF axis Cell Death & Disease