Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Anti cancer therapeutic strategies based on HGF MET, EpCAM, and tumor stromal cross talk Cancer Cell International Springer Nature Link HGF c MET pathway in cancer: from molecular characterization to clinical evidence Oncogene Correlation between hypoxia and HGF c MET expression in the management of pancreatic cancer ScienceDirect The illustration of the molecule mechanism of HGF c Met downstream Download Scientific Diagram
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dihexa hgf/c-met agonist Targeting HGF/c-MET signaling to regulate the tumor microenvironment: Implications for counteracting tumor immune evasion | Cell Communication and Signaling