1 vape = 8 packs of cigarettes?! Yep, you read that right. Many vapes contain as much nicotine as an entire carton of cigarettes. That's a LOT of addiction packed into How many cigarettes equal one vape? A single vape cartridge can have the nicotine equivalent of 600 cigarettes. Most people don't realize how much nicotine is packed into a single vape. Flavors and smooth hits can make it feel harmless, which is why so many young people struggle to How Many Puffs of Vape Equal a Cigarette?