If you have MTHFR , or think you might , this is the most important connection in this series. MTHFR is a gene mutation that impairs methylation. And methylation is the APLB Glutathione Niacinamide Toner Pad OLIVE YOUNG Global APLB Glutathione Niacinamide Facial Toner Toners Ksisters First Time Using APLB's Glutathione Niacinamide Toner MTHFR Affects Detoxification Documenting Hope