PDF] 17 Glucose 6 Phosphate Dehydrogenase Defi ciency Semantic Scholar File:Glutathion metabolism DE state in G6PD deficiency.png Wikimedia Commons File:Pathology of G6PD deficiency.png Wikimedia Commons Glucose 6 Phosphate Dehydrogenase an overview ScienceDirect Topics Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst