NAcetylcysteine (NAC) is More Than Just an Antidote. NAC replenishes glutathione (GSH), breaks mucus disulfide bonds, and modulates glutamate. That's why it works in the liver, lungs, and brain. Owais When Tylenol (acetaminophen) is not properly metabolized, it creates a toxic biproduct. The process to metabolize acetaminophen is called glucuronidation. This process is underdeveloped in young babies. Can Tylenol (acetaminophen) deplete glutathione levels in the body? L Glutamine Administration Reduces Oxidized Glutathione and MAP Kinase Signaling in Dystrophic Muscle of mdx Mice Pediatric Research PDF] Antidote for acetaminophen poisoning: N acetylcysteine Semantic Scholar