Diseases with Documented Low Glutathione [70]. Download Scientific Diagram https: pubmed.ncbi.nlm.nih.gov 32463221 # The National Library of Medicine posted : Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID 19 Patients Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity Nature Communications Sirona's Glutathione deficiency can lead to a variety of signs and symptoms that affect your overall health. Here are some common signs to look out for: 1. **Increased Dark Spots** Glutathione deficiency induces epigenetic alterations of vitamin D metabolism genes in the livers of high fat diet fed obese mice Scientific Reports