Three dimensional structure of a mammalian thioredoxin reductase: Implications for mechanism and evolution of a selenocysteine dependent enzyme PNAS Structure and mechanism of mammalian thioredoxin reductase: The active site is a redox active selenolthiol selenenylsulfide formed from the conserved cysteine selenocysteine sequence PNAS Frontiers Assigning function to active site residues of Schistosoma mansoni thioredoxin glutathione reductase from analysis of transient state reductive half reactions with variant forms of the enzyme Evolutionarily Conserved Role of Thioredoxin Systems in Determining Longevity GSH glutaredoxin and thioredoxin systems. Yeast contains two gene pairs Download Scientific Diagram