FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect FOXO4 peptide targets myofibroblast ameliorates bleomycininduced pulmonary fibrosis in mice through ECMreceptor interaction pathway Han 2022 Journal of Cellular and Molecular Medicine Wiley Online Library The FOXO4 peptide in a DRI conformation (D amino acids in a retro reversed sequence), henceforth named FOXO4 DRI, competes with FOXO4 for p53 binding in a dose dependent manner and doing so with higher affinity. FOXO4 DRI 10mg Ion Peptide FOXO4 DRI (Proxofim) (10mg)