Melanotic macule detected in the buccal mucosa of the patient who Download Scientific Diagram Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in smokers, after Summit Enlighten Laser to treat labial melanotic macules on the lip before and after. Facebook Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a Venous Lake of Lip and Lip Freckle Removal with Iridex Laser