Histamine Intolerance and Mental Health Natural Treatment Amazon.com: Seeking Health Histamine Nutrients Seasonal Histamine Support Supplement with Vitamin B1, Zinc, & Vitamin B3 Aids Histamine Response 60 Capsules : Health & Household Nutrition for Anxiety and Depression: Histamine and Common Allergies Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione. Histamine and TH2 cytokines regulate the biosynthesis of cysteinyl leukotrienes and expression of their receptors in human mast cells Inflammation Research Springer Nature Link