This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding Labial melanotic macule Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a Melanotan II nose spray Salty Skin Store This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips.