Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update Simple cryosurgical treatment of the oral melanotic macule ScienceDirect Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Comment below Pigmented Lesions of the Oral Mucosa Springer Nature Link