Item Scheme showing the enzymatic reactions that catalyze the pyruvate dehydrogenase complex, including pyruvate dehydrogenase activity and diaphorase activity of DLD (A) as well as the glutathione reductase peroxidase activity (B). Frontiers Assigning function to active site residues of Schistosoma mansoni thioredoxin glutathione reductase from analysis of transient state reductive half reactions with variant forms of the enzyme Glutathione Related Enzyme System: Glutathione Reductase (GR), Glutathione Transferases (GSTs) and Glutathione Peroxidases (GPXs) Springer Nature Link Conversion oxidized glutathione (GSSG) to the reduced form (GSH) by Download Scientific Diagram Structure and mechanism of mammalian thioredoxin reductase: The active site is a redox active selenolthiol selenenylsulfide formed from the conserved cysteine selenocysteine sequence PNAS