Application of glutathione depletion in cancer therapy: Enhanced ROS based therapy, ferroptosis, and chemotherapy ScienceDirect Tumor targeted glutathione oxidation catalysis with ruthenium nanoreactors against hypoxic osteosarcoma Nature Communications Glutathione Depletion and Stalwart Anticancer Activity of Metallotherapeutics Inducing Programmed Cell Death: Opening a New Window for Cancer Therapy ACS Omega Role of GSH in carcinogenesis . Glutathione has been shown to regulate Download Scientific Diagram Glutathione is a critical soldier in our line of defense. We even have mechanisms that recycle and reuse it. But what happens when our toxic burden becomes too high? Our genetic detoxification