When people think about detox, they usually think about the liver. But detoxification actually involves several systems working together. One of the most important is methylation. Methylation supports processes involved in Methylation: An Ineluctable Biochemical and Physiological Process Essential to the Transmission of Life The interplay between oxidative stress and epigenetic reprogramming in cancer Ma 2025 International Journal of Cancer Wiley Online Library Methylation as a key regulator of Tau aggregation and neuronal health in Alzheimer's disease Cell Communication and Signaling Springer Nature Link Methylation cycle hypothesis MEpedia