Viral 'Barbie drug' for tanning can cause brain swelling and even cancer, experts warn Melanotan II Wikipedia Avoid nasal tanning sprays or nasal tanners entirely. These products promise an all over tan without sun exposure but they are unregulated, can be unsafe, and contain potentially risky substances like Melanotan 2. There are two peptides people talk about for tanning: Melanotan 1 and Melanotan 2. Melanotan 1 works slower and mainly targets the skin, leading to a more gradual and even increase in Melanotan 1: mechanisms of action, clinical applications and safety_Chemicalbook