Labial Melanotic Macules in Two Pediatric Patients of Chinese Descent With Atopic Dermatitis Katsiaunis 2025 Pediatric Dermatology Wiley Online Library a Melanotic macule at the wetdry line of the lower lip. b Melanotic Download Scientific Diagram Mucosal melanocytic macules Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Mara Ever wondered what those little brown spots are that are often found on the lip? Many refer to them as a freckle but the medical term is melanotic macules.