Can L Glutathione Support Energy and Detoxification in Long COVID and ME CFS? RTHM Glutathione is a critical soldier in our line of defense. We even have mechanisms that recycle and reuse it. But what happens when our toxic burden becomes too high? Our genetic detoxification Glutathione: The Master Antioxidant Core Med Science Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis ScienceDirect Glutathione reductase Wikipedia