A study from the Birsoy lab showed that the antioxidant glutathione, when operating inside mitochondria, is a key factor enabling tumors to spread from the breast to the lung. #RockefellerScience #YearInReview Decreased glutathione biosynthesis contributes to EGFR T790M driven erlotinib resistance in non small cell lung cancer Cell Discovery Frontiers A prognostic signature of Glutathione metabolism associated long non coding RNAs for lung adenocarcinoma with immune microenvironment insights Glutathione in cancer progression and chemoresistance: an update in: Redox Experimental Medicine Volume 2023 Issue 1 (2023) Frontiers Glutathione responsive and exhausting metal nanomedicines for robust synergistic cancer therapy
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