Frontiers FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect Buy FOXO4 DRI Peptide 99%+ Pure FOXO4 DRI for Research FOXO4 DRI (10MG)INJECTION, Packaging Type: Vial at 3200 piece in Nagpur The FOXO4 peptide in a DRI conformation (D amino acids in a retro reversed sequence), henceforth named FOXO4 DRI, competes with FOXO4 for p53 binding in a dose dependent manner and doing so with higher affinity.