Simultaneous quantification of trimethylamine oxide and its precursors from gut microbial metabolic pathway Assembling the anaerobic gamma butyrobetaine to TMA metabolic pathway in Escherichia fergusonii and confirming its role in TMA production from dietary L carnitine in murine models mBio Identification of TMAO producer phenotype and hostdietgut dysbiosis by carnitine challenge test in human and germ free mice Gut This #GUTRecentAdvancesInBasicScience review synthesises emerging evidence linking the microbiome to cardiovascular disease, highlighting shared inflammatory and metabolic pathways. Fusco et al. present Gut microbiota and atherosclerosis access it Intestinal microbiota metabolism of l carnitine, a nutrient in red meat, promotes atherosclerosis Nature Medicine