Pigmented Lesions of the Oral Mucosa Springer Nature Link Gray melanotic macule on the palate in a 50 year old female Download Scientific Diagram Figure 1 from Oral melanotic macule a case report. Semantic Scholar Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI