Glutathione for Thyroid Health Victoriahealth.com Ltd Full article: An increase of oxidative stress markers and the alteration of the antioxidant enzymatic system are associated with spleen damage caused by methimazole induced hypothyroidism Glutathione is the body's primary internal antioxidant, made using the amino acid cysteine, and it helps protect cells from oxidative stress. Beyond detoxification, research shows glutathione is involved in thyroid hormone metabolism, How to Increase Glutathione to Protect Against Hashimoto's Role of Glutathione in Cancer: From Mechanisms to Therapies