You Need More Riboflavin with G6PD Deficiency! G6PDHelp.com Pathology of G6PD deficiency Pathology Made Simple Glucose 6 phosphate dehydrogenase deficiency McMaster Pathophysiology Review Glucose 6 phosphate dehydrogenase deficiency and risk of cardiovascular disease: A propensity score matched study Atherosclerosis In RBCs, NADPH are produced exclusively via HMP shunt by the action of G6PD and are responsible to maintain membrane integrity preventing premature destruction. That is why G6PD deficient RBCs are