The Metabolism of Acetaminophen and the Synthesis of Glutathione Download Scientific Diagram The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism William Parker, Chi Dang Hornik, Staci Bilbo, Zoie E. Holzknecht, Lauren Gentry, Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize Taking Tylenol? The Glutathione Connection Dr. Green Mom Sex differences in glutathione metabolism and acetaminophen toxicity