One of the biggest concerns Lyme disease patients have when beginning treatment is whether or not they will have a herxing response. In fact, it's one of the most common questions I Feeling worse before you feel better? It might be a Herx. Also called a Jarisch Herxheimer reaction, herxing happens when Lyme microbes are killed off and release toxins into your system, sparking a Amazon.com: Allergy Research Group ThioDox Supplement Glutathione Complex, L Glutathione with Vitamin C, NAC, Alpha Lipoic Acid, Tablets 90 Count : Health & Household Glutathione Injections: Side Effects & Benefits LYME SCI: The dreaded Jarisch Herxheimer reaction