Pigmentation is regulated in two places: internally, and at the skin level. This is the systemic side of the equation. Oxidative stress, inflammation, detoxification capacity, and internal signaling influence how melanin is The Science Behind a Topical Glutathione Delivery System Ravi Patel, MD, FAAD Dermatology Kelsey Seybold Clinic Topical Absorption of GlutathioneCyclodextrin Nanoparticle Complex in Healthy Human Subjects Improves Immune Response against Mycobacterium avium Infection Dilan A. Patel, MD WashU Medicine Physicians