Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 Oral Pathology: Pigmented Lesions Flashcards Quizlet Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Dermpath Made Simple Neoplastic: Oral Tumours inside cheek Keyword Search Science Photo Library