Immune mechanisms in acetaminophen induced acute liver failure Krenkel HepatoBiliary Surgery and Nutrition Alcohol and paracetamol are both processed through the liver. Paracetamol can form a toxic metabolite called NAPQI, which the body usually neutralises safely. But factors like heavy alcohol use, repeated dosing, fasting, 3 Glutathione Rescue Normally, glutathione binds NAPQI and converts it into non toxic byproducts (cysteine + mercapturic acid) that are excreted. Example: Glutathione is your liver's safety net against toxins. Acetaminophen hepatic metabolism #medschool #medstudent #medstudentlife #medicalmnemonics #nurses #usmle #usmlestep1 #usmlestep2 #usmlestep #medicaltalks #medicalstudent #medicalmemes #medicallife #medicalmotivation #usmlepreparation #medreview Tox and Hound Fellow Friday What Terror Hath NAPQI Wrought?