Pharmacological Activation of the Melanocortin System Limits Plaque Inflammation and Ameliorates Vascular Dysfunction in Atherosclerotic Mice Arteriosclerosis, Thrombosis, and Vascular Biology Transformation of a benign oral pigmentation to primary oral melanoma ScienceDirect Melanotan II A Sun Kissed Look, and a Confident You. Melanotan 2 Cyclic Heptapeptide for Melanocortin Research Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a