I've posted this every year for 7 years. PSA please share. The horror stories from Tylenol (Acetaminophen) usage for children are hard to digest literally. The way my mind Tylenol's Impact on Glutathione and Liver Damage Acetaminophen Anesthesia Key Tylenol Avoid or Not to Avoid? Acetaminophen (Tylenol) can deplete glutathione, your body's most important detox antioxidant. This matters even more if your child has an MTHFR gene mutation, which Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: