Glucose 6 phosphate dehydrogenase (G6PD) deficiency X linked recessive Xq28 is not true recessive as heterozygotes can express the trait; G6PD > No NADPH > No RBC glutathione protection > free radical damage hemolysis G6PD Deficiency Oxidative Stress Induced Hemolysis Mini MCAT passage: Pentose phosphate pathway and G6DP deficiency (practice) Khan Academy Figure 2 from Impact of glucose 6 phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease. Semantic Scholar Glucose 6 Phosphate Dehydrogenase Deficiency Symptoms, Pathophysiology, Diagnosis and Treatment