Coffee enemas are an effective detoxification therapy we offer at Hope4Cancer Treatment Centersused both at our treatment centers and as part of our at home protocols. While they may seem unconventional, their effectiveness Antioxidant effects after coffee enema or oral coffee consumption in healthy Thai male volunteers S Teekachunhatean, N Tosri, C Sangdee, R Wongpoomchai, W Ruangyuttikarn, C Puaninta, S Srichairatanakool, 2012 Coffee enemas: are there health benefits? A coffee enema is a natural detoxification therapy in which brewed organic coffee is introduced into the colon through the rectum. This process stimulates the liver and gallbladder, promoting bile flow and Is the buzz around coffee enemas boosting glutathione levelssometimes claimed to increase them by 600 700% true?