Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic Melanotan 1 (MT1) Therapy: Realistic Results and Expectations Peptide Dosage 50+ reels on Instagram 30 year old man with painless hyperpigmentation on buccal mucosa of a few months duration. Relatively stable in terms of size. Mirror lesion on other cheek. No history of trauma or smoking.