Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Frontiers Mucosal Melanoma: Pathological Evolution, Pathway Dependency and Targeted Therapy Labial melanotic macule Melanotic Macules, Naevi, and Melanoma Springer Nature Link Malignant melanomacutaneous and mucosal. a, b Melanoma of the right Download Scientific Diagram