Labial melanotic macule (brown spot on lip) (Stony Brook Case 1) dermatology dermatopathology Melanotic Macules, Naevi, and Melanoma Springer Nature Link Spotty lips. These are labial melanotic macules, kinda like freckles on the lips. They are mostly due to age and sun exposure, but sometimes they run in families and are associated with Oral melanotic macule and primary oral malignant melanoma: Epidemiology, location involved, and clinical implications Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics Labial melanotic macule